LEAD OPTIMIZATION
Our Services
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Lead Optimization
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Our Services Includes
01
High-Throughput Screening (HTS)
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High-throughput screening (HTS) capabilities to rapidly test large libraries of lead compounds against specific biological targets.
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Development and validation of custom assays, allowing for the efficient identification of lead candidates with the desired biological activity.
02
PK and PD Optimization
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Optimization of pharmacokinetic (PK) and pharmacodynamic (PD) profiles of lead compounds to ensure they have suitable absorption, distribution, metabolism, and excretion properties.
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Optimizing dosing regimens, bioavailability, and half-life, as well as enhancing the therapeutic efficacy and safety profile of the candidates.
03
Structure-Activity Relationship (SAR) Analysis
04
In Silico Modelling and Predictive Analytics
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in-depth Structure-Activity Relationship (SAR) analysis to refine and optimize lead compounds.
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systematically modification of chemical structures to enhance potency, selectivity, and overall therapeutic index while reducing potential off-target effects.
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Computational modeling and predictive analytics services to simulate and predict the behavior of lead compounds in biological systems.
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Molecular docking studies, pharmacophore modeling, and predictive ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis to identify and optimize the most promising candidates for further development.